[4] Flavin Adenine Dinucleotide Photochemistry Is Magnetic Field Sensitive at Physiological pH

Published in The Journal of Physical Chemistry Letters, 2018

Recommended citation: Lewis M. Antill and Jonathan R. Woodward (2018). "Flavin Adenine Dinucleotide Photochemistry Is Magnetic Field Sensitive at Physiological pH." The Journal of Physical Chemistry Letters, 9, 10, 2691-2696. https://pubs.acs.org/doi/abs/10.1021/acs.jpclett.8b01088

We present time-resolved optical absorption and magnetic field effect data on the photochemistry following blue light excitation of flavin adenine dinucleotide (FAD) in aqueous solution in the pH range 2.3 to 8.0. Effects of closed form conformations of FAD in ground, excited singlet, and radical pair states exhibit significant influence on the observed kinetics and magnetic field dependence and remarkably, magnetic field effects are observed even at physiological pH where the FAD radical pairs are only 75% less magnetic field sensitive than at pH 2.3.